I'd like this to be a comprehensive thread discussing marijuana and anti-depressants. Long story short, all my life I have been severely depressed. I'm not complaining, but I must admit, I have been dealt a shittier hand than many in life. I am grateful for what I do have, don't get me wrong, but I am skeptical about my true happiness and if I am lying to myself when I say I am 'content'. I have been on and off a variety of antidepressants since I was around 13 years old. The doctor I was seeing at the time gave me high doses (adult doses) and if one medication didn't seem to work after some time would simply switch me to another. I quit taking them when I turned around 17 because I felt like they were hurting me more than they were helping. For about a year and a half I self-medicated on any and all drugs until I had a complete meltdown. It was a revelation that couldn't have come at a better time, and although negative in reflection it was perhaps the most positive progression in my life. I have since quit self medicating myself with drugs and gotten rid of my desire to be 'out of it' all the time, but the urge is creeping back. My family has a long history of substance abuse and drug dependency so I think this has something to do with it. I've noticed in the past months my marijuana usage has slightly increased, as my depression begins to set back in. The gloomy, foggy, rainy days of Fall in Southeast Alaska don't help at all either and I fear when the dark and frigid winter sets in it may get worse... I've begun limiting myself to only getting high when I feel like I can enjoy myself and have a productive experience rather than just getting high to get high. I've never contemplated trying anti-depressants again until the past few days. It's been in my mind for weeks now, but I think I am at a point where I am ready to give it another go. I have setup an appointment with a local psychiatrist and within the next few days will be meeting with him. I plan to be open and honest about my past and current drug use. I'm skeptical about going back on the 'meds, but at this point in my life, I'm open for change and I want to get better. What I want to know, if anyone has any information, anecdotal or scientific, in regards to their particular antidepressants and their marijuana use; the effects between the two, their marijuana useage/particular prescription, studies, etc. Any and all information is greatly appreciated and others questions are welcome. However, I would not like this thread to be a debate about biomedical psychology. Thank you for your responses.