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Old 12-17-2006, 09:20 AM   #1
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Default CAN: Synthetic Marijuana Helps Cancer Patients: Study

Synthetic Marijuana Helps Cancer Patients: Study
12.15.06|Reuters|By Deena Beasley

A synthetic version of the active ingredient in marijuana, a legal treatment for nausea in cancer patients undergoing chemotherapy, also helps symptoms like pain, anxiety and depression, according to research presented on Friday.

"The findings show how great the potential is to improve the quality of life for cancer patients," said lead investigator Dr. Vincent Maida of the University of Toronto.

The 139-patient study involved a drug called nabilone, sold under the brand name Cesamet by Valeant Pharmaceuticals International. It has been available in Canada for years, and was approved in May by the U.S. Food and Drug Administration for patients who have failed to respond adequately to conventional anti-nausea treatments.

The drug is part of a class known as cannabinoids that are similar to the active ingredient found in naturally occurring cannabis, or marijuana.

But Cesamet, as with similar drugs such as Solvay SA's Marinol, is designed to target specific cannabinoid receptors and does not carry the toxic effects associated with smoking marijuana, Maida said.

"This is not the pot pill," he said. "It has absolutely no street value."

That contrasts with morphine-based pain drugs, such as OxyContin, that are associated with addiction and abuse, the investigator said.

The study, based on questionnaires filled out by cancer patients, found that those treated with the drug experienced significantly more pain reduction than patients treated with standard therapy. Scores for drowsiness, tiredness, appetite and well-being were stable in the Cesamet group, but deteriorated in the non-Cesamet group.

Depression and anxiety were also reduced significantly in the nabilone group, but increased in the non-cannabinoid group, according to the study, which was presented at the San Antonio Breast Cancer Symposium.

"There are no other drugs that are as broad-spectrum as cannabinoids. By using them, we can reduce the use of other drugs which are riskier, burdensome and expensive," Maida said.

Side effects of Cesamet include drowsiness, dizziness, dry mouth and euphoria.

But Valeant's sales of the drug, which was launched in the United States in August, totaled just $7.3 million in the first half of this year.

"The issue is the stigma," Maida said. "There is some timidity on the part of practitioners to prescribe these drugs."
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Old 12-17-2006, 02:14 PM   #2
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Default

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But Cesamet, as with similar drugs such as Solvay SA's Marinol, is designed to target specific cannabinoid receptors and does not carry the toxic effects associated with smoking marijuana, Maida said.
Such as???

Quote:
"There are no other drugs that are as broad-spectrum as cannabinoids. By using them, we can reduce the use of other drugs which are riskier, burdensome and expensive," Maida said.
Maida, come register with us..
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Old 12-17-2006, 03:28 PM   #3
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"...does not carry the toxic effects associated with smoking marijuana, Maida said....

Such as???"
Getting arrested and tossed in jail?

Now if you think a few days in jail is not 'toxic' google "Jonathan Magbie".
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Old 12-17-2006, 11:11 PM   #4
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Default Pills!!!

[size="3"] The pharmacetical company is proud of copying qualities found in MJ...wonder how much money they sank into that crap... synthesizing THC effects but eliminate the euphoria...now why the hell do they want that? Just use the real thing and save yourself from all the side effects...I for one have experienced side effects from several of my medications...and it sucks when it puts u in the hospital!!! Because of fu***king presriptions for pills!!!!!!!!! /SIZE]
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Old 12-18-2006, 12:53 AM   #5
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But Cesamet, as with similar drugs such as Solvay SA's Marinol, is designed to target specific cannabinoid receptors and does not carry the toxic effects associated with smoking marijuana, Maida said.

"This is not the pot pill," he said. "It has absolutely no street value."
Bullshit! Cesamet and Marinol will get you higher than a kite. This is a "side effect" that annoys many of the people who are prescribed these drugs. Both are synthetic THC and work in exactly the same way as natural THC. All three of them activate the CB1 receptors. As with any orally administered THC, effects don't become apparent for an hour at which point you might find that it wasn't enough to deal with your symptoms or it was too much and you're too high to function well.
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