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Old 01-26-2004, 12:21 AM   #1
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Default Pot's longterm affect on the brain

I was in a discussion with someone that gave me this argument from a book of theirs. Has anyone ever heard this?


"I found out that THC attaches to fat, ergo making it fat soluble. I am sure you know or will learn that it takes a long time, if ever, to reach fat stored in the body. You may not know that there is a large amount of fat storage in the brain. Over time, the build up of THC attaches to the fat in the brain in the area of the synapse eventually causing signals to misfire. The taking of any drug has an insidious effect, thereby confusing us into thinking we aren't really doing any harm. I would like to caution you that your dalliance with THC will eventually and with certainty, cause you harm both personally and professionally."


What do you guys think?
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Old 01-26-2004, 12:22 AM   #2
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To the Chemical and Physiological forum.

---

This is Reefer Madness.

What's the name of the book?
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Old 01-26-2004, 12:32 AM   #3
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I'm no neurologist but i've NEVER heard of fat storage in the brain
except from reefer-mad stories like that. Until someone with a
degree tells me otherwise, i'm going to dismiss that argument as
a COMPLETE load of crap.

Quote:
You may not know that there is a large amount of fat storage in the brain
Tricky, tricky. The article never explicitly SAYS that a large amount
of fat storage is in the brain, but that you might not know it. You
can't know something that's not true is it?


===============
OK i've done some googling and the brain *is* around 70% fat.

That's not to say that it isn't a scare tactic loosely backed with an
otherwise trivial fact.

Also, a scientific study that proves THC bonds to the fat in the
brain and causes permanent problems would be so irresistable to
the reefer-mad that we'd all have heard it.

EDIT: Yeah, i want the book too. Maybe there are footnotes or a bibliography.
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Old 01-26-2004, 12:41 AM   #4
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Thumbs down

I would think the only "thc" held in fat cells are non-psychoactive thc metabolites that would have no adverse effect at all on brain function.

The "Society for Neuroscience" has this to say...


In radioactive tracing studies, scientists found that tetrahydrocannabinol (THC), the active ingredient in marijuana, binds to specific receptors, many of which coordinate movement. Thismay explain why people who drive after they smoke marijuana are impaired. The hippocampus, a structure involved with memory storage and learning, also contains many THC receptors. This may explain why heavy users or those intoxicated on marijuana have poor short-term memory and problems processing complex information. Scientists recently discovered that these receptors normally bind to a natural internal chemical
called anandamide, and are now working to see how this natural
marijuana affects brain function.
---------------------------------------

I highly doubt these receptors are going to react from thc metabolites stored in your fat cells. The receptors are effected when your high.

Also note that it only mentions that there are receptors present but not their actual reaction to thc. Any reaction or effect to these receptors are merely postulated.
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Old 01-26-2004, 02:09 AM   #5
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One thing that's not too relevant but reflects on this person's
credibility is that fat in the brain is not stored, but IS the brain.
It's not lard, it's your brain and it just happens to be made of fat.
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Old 01-26-2004, 06:10 PM   #6
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I appreciate the responses guys. Definately some good counterarguments there, some of which I'll certainly use if noone objects.
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Old 01-27-2004, 04:12 PM   #7
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Long term effect on the brain?


Protects the brain from the "cascade effect" caused by brain traumas...

Has been known to save the lives and function of stroke patients

Protects against certain bio-chemical weapons that cause brain damage...

Pretty good stuff...

...anyone want a cookie?

Hugz,

Mama Budz
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Old 01-27-2004, 04:33 PM   #8
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Quote:
Originally posted by Mamabudz
Protects against certain bio-chemical weapons
Now I know why it's illegal, weed is top secret military soft-ware, wouldn't want terrorists protecting themselves now would we?

Sure I'll have a cookie Peace.
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Old 01-27-2004, 04:43 PM   #9
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In 1998 U.S. Army tests, rats injected with Dexanabinol, Pharmos’ synthetic version of cannabidiol, (CBD) one of the constituents in whole cannabis, were more than 70 percent less likely to suffer epileptic seizures or brain damage after exposure to sarin and other nerve gases...

Yup...you're right!

...have another cookie
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