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Old 05-18-2006, 12:09 AM   #1
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Default MJ/Bipolar drug reaction?

this is kind of a continuation of a previous post concerning Lamictal and marijuana (http://www.marijuana.com/420/showthread.php?t=41048). I quit smoking more than a year ago, and just started again recently. In the time that I have abstained, I have had my medications for bipolar disorder changed to lamictal and amytriptoline. I have noticed that my highs aren't that great now that I've started up again. Instead of everything being humorous, etc, and all that comes with a good buzz, my highs have been rather crappy experiences. I get paranoid, my body hurts, and everything seems in a painful, trippy slow motion. Last night I got really sick from a hit on a gravity bong (believed to be a panic attack). I started tripping really bad, threw up, and passed in and out of consciousness. I was in so much pain I wanted to die, and thought I would. Heart palpitations, uncontrollable twitching, sweating, the whole works. I thought I would have a heart attack, and felt that I was falling and being crushed by a large weight (I know these two things can't really happen at the same time, but it's how I felt.) I also felt like I was going to lose control of my bodily functions, and piss myself. I couldn't walk without help, like I was really drunk. To sum it up, it was a bad high.
What I want to know is, could my meds be affecting my high? Was my really bad high last night just a panic attack, or could it be something else? I'm still sick from it, almost a day later, and still feel like I'm fading in and out of an alternate reality. Please help, thanks
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Old 05-18-2006, 08:45 AM   #2
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It has everything to do with your meds. It sounds to me like it was a bad panic attack, but yeah, I would say with a pretty high level of certainty that it's the meds.

I'm sure someone else here will be able to go into much more detail, but I just thought I'd give you a quick response. Meds fuck with your brain, bottom line.
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Old 10-13-2007, 11:52 PM   #3
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Unhappy I feel the same way

I used to have those highs were everything is funny and u just laugh like crazy and u feel like ur floating.

Ever since this one incident, i dont get those highs anymore

The incident was, i ate 1/2 gram and passed out. It was the most painful i have ever gone through. Every heart beat was like needles shooting into my heart. i honestly expected to have a heart attack. After waking up from passing out i vomitted several times and felt like shit for a few days.

Ever since then i notice that my highs are NEVER happy funny laughing kinds of highs.
I always thought it was the different breeds of weed, but i noticed that its only happened since this incident.

I think my body interprets it differently now i guess.

Now my highs are like, i just want to sit there and stare and not say anything. If I get really high, then i want to get out of the high so bad! It is painful in my chest/heart and i talk really quietly and i dont want to talk or anything. I hate it! it sucks so bad. I wish i could cleanse my body and restart so i have the good old days highs again. :-(
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Old 10-14-2007, 12:10 AM   #4
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I wish i could cleanse my body and restart so i have the good old days highs again
Most likely you can, but you'll have to quit your meds for a while. Have you ever considered treating your condition with marijuana alone?
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Old 10-15-2007, 03:06 PM   #5
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stop the weed and wait till your meds balance out in your system. Try to smoke a small amount of pot. If you have any probs with your well being then by all means quit and get a health check up.You will have to decide to stop smoking or drop the meds. If I personnally dropped my meds. Nobody could be around my manic episodes or I would not get outta bed for days. I do hope it all works out for you and good luck.
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Old 10-15-2007, 03:10 PM   #6
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Forgot to mention: talk to your shrink
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Old 10-15-2007, 03:19 PM   #7
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It might have something to do with the medications. But you might be following into a pattern. You expect the same bad thing to happen to you, so it does.
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Old 10-16-2007, 03:29 AM   #8
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Having taken amitriptyline for awhile, I could almost say for sure that it is the problem. The feelings and moods that you describe are identical to what I experienced with it.

Lamictal is a more benign drug, and is also a newer drug. Amitriptyline is an old drug, so I would ask the doc to maybe switch you off to something newer, because there are newer and better drugs on the market.......

But, as I always say, consult with your doctor before making any decisions one way or the other. Better to be safe than sorry.......


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Old 10-20-2007, 09:57 PM   #9
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Quote:
Originally Posted by triggerfinger View Post
this is kind of a continuation of a previous post concerning Lamictal and marijuana (http://www.marijuana.com/420/showthread.php?t=41048). I quit smoking more than a year ago, and just started again recently. In the time that I have abstained, I have had my medications for bipolar disorder changed to lamictal and amytriptoline. I have noticed that my highs aren't that great now that I've started up again. Instead of everything being humorous, etc, and all that comes with a good buzz, my highs have been rather crappy experiences. I get paranoid, my body hurts, and everything seems in a painful, trippy slow motion. Last night I got really sick from a hit on a gravity bong (believed to be a panic attack). I started tripping really bad, threw up, and passed in and out of consciousness. I was in so much pain I wanted to die, and thought I would. Heart palpitations, uncontrollable twitching, sweating, the whole works. I thought I would have a heart attack, and felt that I was falling and being crushed by a large weight (I know these two things can't really happen at the same time, but it's how I felt.) I also felt like I was going to lose control of my bodily functions, and piss myself. I couldn't walk without help, like I was really drunk. To sum it up, it was a bad high.
What I want to know is, could my meds be affecting my high? Was my really bad high last night just a panic attack, or could it be something else? I'm still sick from it, almost a day later, and still feel like I'm fading in and out of an alternate reality. Please help, thanks

I have bipolar syndrome as well, and I am also on amitriptyline, although my doctor / psychiatrist have taken me off of amitriptyline for anti-psychotics (please don't ask). I can say I've felt almost the exact same as you have, although strangely enough, while not doing pot. I find I can still smoke bud without having any bad reaction, but after I sober up I'll have a similarily described episode, minus the high.
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