Marijuana.com

Carlos

Does anybody know what the effect of pot is on your liver??? and do you think that you should smoke it if you've had liver failure recently ???

 

Mamabudz

There have been studies that cannabis and cannabinoids would prove benficial in the treatment of pain associated with liver ailments.

Without more information it is difficult to answer your question more completely.

I would suggest a search on Google or yahoo using the terms "liver" and cannabis" or "cannabinoid" (as opposed to "pot" or "marijuana") as these terms will bring up more of the current medical science and journal information currently on the web.

And you should be frank with your doctor about your marijuana useage if there is an underlying condition. Your doctoer may not agree with your using it but he/she should be straightforward with you on the facts of your condition to the best of their ability to explain and your ability to understand.

Hope you do well and good luck

Mama Budz

poolman950

Heh, since the liver's main function has to do with removing toxins from food and drink, I don't see how smoking weed could possibly damage it. I suppose if THC was toxic or harmful in some way (which, in case you've had your head up your butt for the last 30 years, it isn't), then it could somehow be transfered by the bloodstream and be damaging...but isn't. Eating weed is the only thing that would even have any POTENTIAL for damaging the liver, and even then, if you cook it properly (eg dont eat it raw ), the chances of any sort of risk are made barely existant.

AnarchistBarbie

I'd also suggest [in addition to Mamabudz great suggestions] using the search features at PubMed - but searching liver won't get you much - search 'cannabis' and 'marijuana' and combine each of those with 'hepatic' [your liver is the main organ in your hepatic system, and hepatic failure is the failure of your liver to continue functioning.] Good luck

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EeJay

THC IS toxic. It doesn't matter if the dose you consume is enough to kill you or cause noticable harm via toxicity, the fact remains that THC IS toxic, I don't know why people keep ignoring this.

It is being pretty technical and some might say, anal, because it's probably very rare that any of us will ever be affected by THC toxicity, but we cannot say it is not toxic. We should say it's toxicity is there, but shouldn't cause problems regarding the liver, or not mention it at all.

Besides, I think by the time THC reaches the liver, if it does at all, it is already inactive.

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Experience is an honest teacher.

 

ikari

depends on your definition of toxic.

under criminal definition, it alters mood and such so yes, it's toxic.

from a more medical perspective, well there's no actual damage, so no, it's not toxic.

if you're referring to the fact that you can OD on it if you (somehow) injected (you cant ever smoke enough) to OD on it... but i mean, so is water is you drink too much... so what does that say?

"everything in moderation" i would hope

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Mamabudz

Sorry EJ but the information you present is not verified in the current information available from moderne (and not so modern) sources.

Unless you have a specific reference to your claim, it will have to be considered simply your belief.

If you have additional information on the "toxicity of THC" please send it over with the URL so it can be added to the files here.

Thanks and have a cookie

Mama Budz

EeJay

Mamabudz

And what EJ is referring to is the following, I'll try to help along the "scientific parts"

TOXICITY
TETRAHYDROCANNABINOL: Toxicity here is the effect on the creature by the THC, ie, how stoned it gets and at what point does it get so stoned that it dies

TOXICITY DATA:
The following is how much each animal must be given (orally, intravenously, or otherwise) to reach 50% of the Lethal Dose or as they say the LD50

666 MG/KG ORAL-RAT LD50; In this example, a 3 kg rat would need almost 2000 mg of THC at one time ORALLY to reach 50% of a dose necessary to kill it

482 MG/KG ORAL-MOUSE LD50;

525 MG/KG ORAL-DOG LDLO;

29 MG/KG INTRAVENOUS-RAT LD50;

42 MG/KG INTRAVENOUS-MOUSE LD50;

128 MG/KG INTRAVENOUS-MONKEY LDLO;

373 MG/KG INTRAPERITONEAL-RAT
LD50;

168 MG/KG INTRAPERITONEAL-MOUSE LD50;

So we see that shooting up rodents with VERY large doses of THC (# of mg of THC over the KG of wt of the creature) is not good for vermin health

REPRODUCTIVE EFFECTS DATA
(RTECS);

MUTAGENIC DATA (RTECS);

TUMORIGENIC DATA (RTECS).

CARCINOGEN STATUS: NONE. <== VERY INTERESTING FINDING

ACUTE TOXICITY LEVEL: MODERATELY TOXIC BY INGESTION. <== No acute toxicity level by ingestion reported

TARGET EFFECTS: CENTRAL NERVOUS SYSTEM DEPRESSANT. <== there is some disagreement on this as THC stimulates appetite and "drug" cannot be both a Stimulant & a Depressant, so this shows that this particular finding is out of date

POISONING MAY ALSO AFFECT
THE RESPIRATORY, CARDIOVASCULAR AND IMMUNE SYSTEMS.

ADDITIONAL DATA: THE USE OF ALCOHOLIC BEVERAGES MAY ENHANCE THE TOXIC EFFECTS.

Drinking will increase the "toxic" effect

POISONING MAY IMPAIR THE PERFORMANCE OF TASKS REQUIRING ALERTNESS.

INTERACTIONS WITH MEDICATIONS HAVE BEEN REPORTED.


So to summarize, if you are referring to TOXICITY as deadly dose taken orally, imbibed as a tea or eaten, even for a rat, you would need a Mega dose to reach a level of even slight concern before the question of overdoseage leasding to death came into play

Remember we aren't doctors or pharmacists, just over educated zealots with an inordinate amount of time on our hands to set the record straight (so to speak) about Cannabis.

Hope that answers your question.

...have a cookie

Mama Budz

EeJay

Wow, that cleared a few things up actually, thanks Mama.