New Study: Marijuana’s CBD Cannabinoid May Protect From Side Effects of Cancer Drugs

Posted by Monterey Bud & filed under marijuana cannabinoids, Marijuana Medicine, marijuana research.

Weed - New Study: Marijuana’s CBD Cannabinoid May Protect From Side Effects of Cancer Drugs

“These results indicate that cannabidiol represents a potential protective agent against doxorubicin cardiac injury”

Another day, another new study! This one published in the journal Environmental Toxicology and Pharmacology noted that everyone’s newest friend, the CBD cannabinoid – a.k.a cannabidiol – and the ‘poster cannabinoid’ for medical marijuana, could very well protect the heart from the dangerous side effects associated with doxorubicin (commonly known as Doxil). Doxil is part of a group of chemotherapy drugs known as anthracycline antibiotics, and has been shown to slow or even halt the growth of aggressive cancer cells.

Within the recent study, the “potential protective effect of cannabidiol, the major non-psychotropic Cannabis constituent, was investigated against doxorubicin cardiotoxicity in rats.”

Scientist  discovered when lab rats were administered small doses of the CBD cannabinoid,  in conjunction with a standard doses of Doxil, there was no detectable heart issues associated with the doxorubicin. Conversely, the lab rats that were exposed to doxorubicin, but not given any CBD cannabinoids, showed signs of notable harm done by the drug.

Abstract:

“The potential protective effect of cannabidiol, the major non-psychotropic Cannabis constituent, was investigated against doxorubicin cardiotoxicity in rats. Cardiotoxicity was induced by six equal doses of doxorubicin (2.5 mg kg−1 i.p., each) given at 48 h intervals over two weeks to achieve a total dose of 15 mg kg−1. Cannabidiol treatment (5 mg kg−1/day, i.p.) was started on the same day of doxorubicin administration and continued for four weeks. Cannabidiol significantly reduced the elevations of serum creatine kinase-MB and troponin T, and cardiac malondialdehyde, tumor necrosis factor-α, nitric oxide and calcium ion levels, and attenuated the decreases in cardiac reduced glutathione, selenium and zinc ions. Histopathological examination showed that cannabidiol ameliorated doxorubicin-induced cardiac injury. Immunohistochemical analysis revealed that cannabidiol significantly reduced the expression of inducible nitric oxide synthase, nuclear factor-κB, Fas ligand and caspase-3, and increased the expression of survivin in cardiac tissue of doxorubicin-treated rats. These results indicate that cannabidiol represents a potential protective agent against doxorubicin cardiac injury.”

Source:

Comments 3 Comments so far... Add Yours

  1. FievelJ

    Seems like no surprise to me, that is would help. Cannabis helps with so many things already. Helps apatite with chemotherapy patients. Good study anyways. ;-)

    Reply
  2. DrSteven

    CBD! A non-psychoactive and very therapeutic substance!

    MJNA/Dixie, a medical marijuana portfolio company just announced today they are as of today shipping internationally their hemp products! And more products to come!

    Time to take marijuana away from the cartels and regulate this substance!
    Youth use goes down when prohibition is lifted and taxes can help this
    economy.

    CBD, cannabidiol, is in both marijuana and hemp (also cannabis).

    How to invest in this economy or get the benefits of cannabis no matter where you live?

    Follow this:

    Hemp is legal to possess in ALL 50 states.

    Legal states for all cannabis (legal thc containing cannabis) are noticing that half of all sales are for edibles and extracts!

    The premier company in the legal state of Colorado is Dixie Botanicals and DIxie Elixers, two companies owned by MJNA.

    MJNA is the alpha source of CBD from legal hemp through their other company RSHO (Phytosphere)!

    MJNA, a stock traded on the stock market is about to rocket up!

    As well for those that want CBD they can order it from ANY state legally from MJNA (phytosphere) or from Dixie Botanicals!

    Invest in the “Green Rush”! MJNA is the ALPHA company to invest in!
    Investing in MJNA is investing in America!
    Help the sick and take cannabis away from the overseas cartels by investing in MJNA!

    Reply
  3. buy marijuana

    Some people might have high expectations of themselves in addition to those around them.
    There was simply no voice released the day before
    the show. ‘ When this device is filled with vapor, the equipment can be turned off.

    Reply

Leave a Comment

or

  • (will not be published)

XHTML: You can use these tags: <a href="" title="" rel=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>

Footer Banner Ad

More in marijuana cannabinoids, Marijuana Medicine, marijuana research (87 of 240 articles)
cannabinoids-CBD-THC