CBD Cannabinoid Halts Tumor Growth: Italian Research Shows Cannabidiol Attacks Glioma Cells | Marijuana

CBD Cannabinoid Halts Tumor Growth: Italian Research Shows Cannabidiol Attacks Glioma Cells

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A recent study from an Italian University and published by the National Institute of Health has reported that marijuana’s cannabidiol – the non-psychoactive CBD cannabinoid – has been shown to have ruthlessly attack tumor cells– prohibiting advancement – by altering “multiple tumoral features and molecular pathways.”

Scientists from the Department of Theoretical and Applied Sciences and the Centre of Neuroscience discovered that; “CBD cannabinoids inhibited U87-MG and T98G cell proliferation and invasiveness in vitro and caused a decrease in the expression of a set of proteins specifically involved in growth, invasion and angiogenesis.

The conclusion of this Italian study was simple; “as CBD is a non-psychoactive phytocannabinoid that appears to be devoid of side effects, our results support its exploitation as an effective anticancer drug in the management of gliomas.”

Enjoy the full abstract…

Abstract

In the present study, we found that CBD inhibited U87-MG and T98G cell proliferation and invasiveness in vitro and caused a decrease in the expression of a set of proteins specifically involved in growth, invasion and angiogenesis. In addition, CBD treatment caused a dose-related down-regulation of ERK and Akt prosurvival signaling pathways in U87-MG and T98G cells and decreased hypoxia inducible factor HIF-1α expression in U87-MG cells. Taken together, these results provide new insights into the antitumor action of CBD, showing that this cannabinoid affects multiple tumoral features and molecular pathways. As CBD is a non-psychoactive phytocannabinoid that appears to be devoid of side effects, our results support its exploitation as an effective anti-cancer drug in the management of gliomas.

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My name is Monterey Bud and I was born in Long Beach and raised on the central coast. I surf, dab, burn and write. I'm a husband, a father and a lifelong consumer of connoisseur grade weed. I have been writing about marijuana strains, science, and politics for Marijuana.com since 2012. A Big Sur cultivator from the pre-helicopter days, I'm a big fan of new strains and breaking news. I can be reached on Twitter @MontereyBud